BDBM622332 N-(1-((4-acetylphenyl)amino)-6-methylisoquinolin-5-yl)-4-aminoquinazoline-8-carboxamide ::US20230312556, Compound 63
SMILES COc1ccc(CNc2ncnc3c(cccc23)C(=O)Nc2c(C)ccc3c(Nc4ccc(cc4)C(C)=O)nccc23)c(OC)c1
InChI Key InChIKey=VQOMPKQOCYATLZ-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 622332
TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Sichuan Kelun-Biotech Biopharmaceutical
US Patent
Sichuan Kelun-Biotech Biopharmaceutical
US Patent
Affinity DataIC50: 5.39nMAssay Description:Assay protocol: the inhibitory effects of the compounds of the present invention on the wild-type BRAF enzyme, mutant CRAF enzyme (RAF1 Y340D and Y34...More data for this Ligand-Target Pair
