BDBM622334 4-amino-N-(6-methyl-1-(p-tolylamino)isoquinolin-5-yl)quinazoline-8-carboxamide ::US20230312556, Compound 65
SMILES COc1ccc(CNc2ncnc3c(cccc23)C(=O)Nc2c(C)ccc3c(Nc4ccc(C)cc4)nccc23)c(OC)c1
InChI Key InChIKey=FBNVUKCXJPPHRE-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 622334
TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Sichuan Kelun-Biotech Biopharmaceutical
US Patent
Sichuan Kelun-Biotech Biopharmaceutical
US Patent
Affinity DataIC50: 4.80nMAssay Description:Assay protocol: the inhibitory effects of the compounds of the present invention on the wild-type BRAF enzyme, mutant CRAF enzyme (RAF1 Y340D and Y34...More data for this Ligand-Target Pair
