BDBM622365 US20230312571, Compound 15::US20230312571, Compound 5

SMILES CC(C)(C)[C@H](NC(=O)C(F)(F)F)C(=O)N1[C@@H]2CC[C@@H](C2)[C@H]1C(=O)N[C@@H](C[C@@H]1CCNC1=O)C#N

InChI Key InChIKey=RJLLYBLMSBFMNO-WGGGBPLMSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 622365   

TargetReplicase polyprotein 1a(2019-nCoV)
Fujian Akeylink Biotechnology

US Patent
LigandPNGBDBM622365(US20230312571, Compound 15 | US20230312571, Compou...)
Affinity DataIC50:  35nMAssay Description:The compound was dissolved in DMSO, and diluted in a 3-fold gradient with Echo655 according to the concentration requirements to 10 concentration poi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(2019-nCoV)TBA
LigandPNGBDBM622365(US20230312571, Compound 15 | US20230312571, Compou...)
Affinity DataIC50:  55nMAssay Description:Inhibition of full length SARS-CoV-2 3CL protease expressed in Escherichia coli BL21 (DE3) using Dacyl-KTSAVLQSGFRKME-Edans fluorogenic peptide as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1a(2019-nCoV)
Fujian Akeylink Biotechnology

US Patent
LigandPNGBDBM622365(US20230312571, Compound 15 | US20230312571, Compou...)
Affinity DataIC50:  94nMAssay Description:The compound was dissolved in DMSO, and diluted in a 3-fold gradient with Echo655 according to the concentration requirements to 10 concentration poi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent