BDBM622494 US20230312576, Compound 219

SMILES CC(=O)Nc1cccc(Oc2cccc(NC(=O)N3CCC(=CC3)c3ncnc4[nH]cc(C)c34)c2)c1

InChI Key InChIKey=DWMTZHKJEKZMNU-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 622494   

TargetLIM domain kinase 1(Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM622494(US20230312576, Compound 219)
Affinity DataKi:  4.93nMAssay Description:Inhibition of LIMK1 and LIMK2. Inhibition of LIMK1 and LIMK2 was measured with Lanthascreen Eu binding assay (Life Technologies). This TR-FRET assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent

TargetLIM domain kinase 2(Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM622494(US20230312576, Compound 219)
Affinity DataKi:  5.46nMAssay Description:Inhibition of LIMK1 and LIMK2. Inhibition of LIMK1 and LIMK2 was measured with Lanthascreen Eu binding assay (Life Technologies). This TR-FRET assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent