BDBM622503 US20230312582, Example Compound Formula (I)

SMILES C[C@H](Cc1cnn[nH]1)OCC(=O)N1Cc2cnc(NC3Cc4ccccc4C3)nc2C1

InChI Key InChIKey=SUJZJMGPGBQJII-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 622503   

TargetAutotaxin(Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM622503(US20230312582, Example Compound Formula (I) | US12...)
Affinity DataIC50: 1.59nMAssay Description:The inhibitory activities of the compounds on the autotaxin enzyme were detected using the Autotaxin Inhibitor Screening Assay Kit (Cayman, 700580). ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetAutotaxin(Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM622503(US20230312582, Example Compound Formula (I) | US12...)
Affinity DataIC50: 1.59nMAssay Description:The inhibitory activity of the compound against the Autotaxin enzyme was detected using the Autotaxin Inhibitor Screening Assay Kit (Cayman, 700580)....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM622503(US20230312582, Example Compound Formula (I) | US12...)
Affinity DataIC50: 9.48E+3nMAssay Description:Full-automatic electrophysiological patch clamp QPatch was used to detect the inhibitory effect of compounds on hERG. Cells used in this test were CH...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent