BDBM623457 US11780845, Example 476

SMILES Cc1cccc(Oc2ccc(cc2)-c2c(-c3ccc(NC#N)cc3)n(C)c3ncnc(N)c23)n1

InChI Key InChIKey=NBMUCYPUXMSNHW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 623457   

TargetFibroblast growth factor receptor 2(Human)
Relay Therapeutics

US Patent
LigandPNGBDBM623457(US11780845, Example 476)
Affinity DataIC50: 100nMAssay Description:Compounds of the present invention were also tested in a FGFR2 Biochemical Caliper Assay. Compounds were prepared in 10 mM DMSO solution and serially...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
US Patent