BDBM623479 US11780845, Example 498

SMILES CC(=C)C(=O)Nc1ccc(cc1)-c1c(-c2ccc(Oc3nccc(CO)n3)c(F)c2)c2c(N)ncnc2n1C

InChI Key InChIKey=WWXZSHUSGDEKEV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 623479   

TargetFibroblast growth factor receptor 2(Human)
Relay Therapeutics

US Patent
LigandPNGBDBM623479(US11780845, Example 498)
Affinity DataIC50: 100nMAssay Description:Compounds of the present invention were also tested in a FGFR2 Biochemical Caliper Assay. Compounds were prepared in 10 mM DMSO solution and serially...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
US Patent