BDBM623515 US11780845, Example 534::US11780845, Example 535

SMILES CC(=C)C(=O)Nc1ccc(-c2c(-c3ccc(Oc4nccc(C)n4)c(F)c3)c3c(N)ncnc3n2C)c(CO)c1

InChI Key InChIKey=ALIUKXAOVKUQIU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 623515   

TargetFibroblast growth factor receptor 2(Human)
Relay Therapeutics

US Patent
LigandPNGBDBM623515(US11780845, Example 535 | US11780845, Example 534)
Affinity DataIC50: 100nMAssay Description:Compounds of the present invention were also tested in a FGFR2 Biochemical Caliper Assay. Compounds were prepared in 10 mM DMSO solution and serially...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
US Patent

TargetFibroblast growth factor receptor 2(Human)
Relay Therapeutics

US Patent
LigandPNGBDBM623515(US11780845, Example 535 | US11780845, Example 534)
Affinity DataIC50: 100nMAssay Description:Compounds of the present invention were also tested in a FGFR2 Biochemical Caliper Assay. Compounds were prepared in 10 mM DMSO solution and serially...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
US Patent