BDBM624420 US11780845, Example 1440::US11780845, Example 1494

SMILES Cc1ccnc(Oc2ccc(cc2F)-c2c3-c4cnc(cc4OCCn3c3ncnc(N)c23)C#C)n1

InChI Key InChIKey=HMOJHTXHSCIYGN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 624420   

TargetFibroblast growth factor receptor 2(Human)
Relay Therapeutics

US Patent
LigandPNGBDBM624420(US11780845, Example 1494 | US11780845, Example 144...)
Affinity DataIC50: 100nMAssay Description:Compounds of the present invention were also tested in a FGFR2 Biochemical Caliper Assay. Compounds were prepared in 10 mM DMSO solution and serially...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
US Patent

TargetFibroblast growth factor receptor 2(Human)
Relay Therapeutics

US Patent
LigandPNGBDBM624420(US11780845, Example 1494 | US11780845, Example 144...)
Affinity DataIC50: 100nMAssay Description:Compounds of the present invention were also tested in a FGFR2 Biochemical Caliper Assay. Compounds were prepared in 10 mM DMSO solution and serially...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
US Patent