BDBM624585 US11780849, Compound 156::[8-(6-chloro-7-methoxyquinolin-4-yl)-2,8- diazaspiro[4.5]decan-2-yl](imino)methyl-lambda6- sulfanone

SMILES COc1cc2nccc(N3CCC4(CCN(C4)S(C)(=N)=O)CC3)c2cc1Cl

InChI Key InChIKey=HABMUAYVHUEAEC-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 624585   

TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Human)
Volastra Therapeutics

US Patent
LigandPNGBDBM624585([8-(6-chloro-7-methoxyquinolin-4-yl)-2,8- diazaspi...)
Affinity DataKi: <3nMAssay Description:Assay 2: Compared to the conditions in Assay 1, this assay has a larger dynamic range and ensures the system is under steady-state conditions by redu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
US Patent

TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Human)
Volastra Therapeutics

US Patent
LigandPNGBDBM624585([8-(6-chloro-7-methoxyquinolin-4-yl)-2,8- diazaspi...)
Affinity DataKi:  30nMAssay Description:Assay 2: Compared to the conditions in Assay 1, this assay has a larger dynamic range and ensures the system is under steady-state conditions by redu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
US Patent