BDBM624594 US11780849, Compound 161b

SMILES COc1cc2nccc(-c3ccc4CCN(Cc4c3)[S@](C)(=N)=O)c2cc1OC

InChI Key InChIKey=FZWDJYPCGXBLDX-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 624594   

TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Human)
Volastra Therapeutics

US Patent
LigandPNGBDBM624594(US11780849, Compound 161b)
Affinity DataKi: <3nMAssay Description:Assay 2: Compared to the conditions in Assay 1, this assay has a larger dynamic range and ensures the system is under steady-state conditions by redu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
US Patent

TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Human)
Volastra Therapeutics

US Patent
LigandPNGBDBM624594(US11780849, Compound 161b)
Affinity DataKi:  640nMAssay Description:Assay 2: Compared to the conditions in Assay 1, this assay has a larger dynamic range and ensures the system is under steady-state conditions by redu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
US Patent