BDBM624736 US11780851, Example 6

SMILES Cc1c2Nc3ncc4c(Br)nn(CCCOc2nn1C1CCOCC1)c4n3

InChI Key InChIKey=IGXUEFODDHUSIQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 624736   

LigandPNGBDBM624736(US11780851, Example 6)
Affinity DataIC50: 2.20nMAssay Description:The LRRK2 kinase was obtained from Invitrogen (Life Technologies Corporation) and comprises residue 970 to 2527 of the full length human wild-type LR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
US Patent

LigandPNGBDBM624736(US11780851, Example 6)
Affinity DataIC50: 8nMAssay Description:The LRRK2 kinase was obtained from Invitrogen (Life Technologies Corporation) and comprises residue 970 to 2527 of the full length human wild-type LR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
US Patent