BDBM624813 US20230321108, Isomer 1 of Example 2

SMILES C[C@@H]1CC(=O)Nc2ncnc(N3CCN([C@H]4C[C@@H]34)C(=O)[C@H](CNC3CC3)c3ccc(Cl)cc3)c12

InChI Key InChIKey=DOJSODPNZWPNBR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 624813   

TargetRAC-gamma serine/threonine-protein kinase(Human)
Nanjing Chia Tai Tianqing Pharmaceutical

US Patent
LigandPNGBDBM624813(US20230321108, Isomer 1 of Example 2)
Affinity DataIC50: 59nMAssay Description:a) first, a compound stock solution (10 mM DMSO solution) was diluted with DMSO to obtain a 100 µM compound solution, the compound solution was dilut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Nanjing Chia Tai Tianqing Pharmaceutical

US Patent
LigandPNGBDBM624813(US20230321108, Isomer 1 of Example 2)
Affinity DataIC50: 442nMAssay Description:a) first, a compound stock solution (10 mM DMSO solution) was diluted with DMSO to obtain a 100 µM compound solution, the compound solution was dilut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetRAC-beta serine/threonine-protein kinase(Human)
Nanjing Chia Tai Tianqing Pharmaceutical

US Patent
LigandPNGBDBM624813(US20230321108, Isomer 1 of Example 2)
Affinity DataIC50: 1.00E+3nMAssay Description:a) first, a compound stock solution (10 mM DMSO solution) was diluted with DMSO to obtain a 100 µM compound solution, the compound solution was dilut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent