BDBM624815 US20230321108, Isomer 1 of Example 3

SMILES CC(C)NC[C@@H](C(=O)N1CCN([C@@H]2C[C@H]12)c1ncnc2NC(=O)O[C@@H](C)c12)c1ccc(Cl)cc1

InChI Key InChIKey=UHWWJBSCMVJFFQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 624815   

TargetRAC-gamma serine/threonine-protein kinase(Human)
Nanjing Chia Tai Tianqing Pharmaceutical

US Patent
LigandPNGBDBM624815(US20230321108, Isomer 1 of Example 3)
Affinity DataIC50: 45nMAssay Description:a) first, a compound stock solution (10 mM DMSO solution) was diluted with DMSO to obtain a 100 µM compound solution, the compound solution was dilut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Nanjing Chia Tai Tianqing Pharmaceutical

US Patent
LigandPNGBDBM624815(US20230321108, Isomer 1 of Example 3)
Affinity DataIC50: 186nMAssay Description:a) first, a compound stock solution (10 mM DMSO solution) was diluted with DMSO to obtain a 100 µM compound solution, the compound solution was dilut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetRAC-beta serine/threonine-protein kinase(Human)
Nanjing Chia Tai Tianqing Pharmaceutical

US Patent
LigandPNGBDBM624815(US20230321108, Isomer 1 of Example 3)
Affinity DataIC50: 771nMAssay Description:a) first, a compound stock solution (10 mM DMSO solution) was diluted with DMSO to obtain a 100 µM compound solution, the compound solution was dilut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent