BDBM624868 1-(4-(2-(5-fluoro-2-(3-((methylamino)methyl)imidazo[1,2-a]pyridin-6-yl)phenoxy)ethyl)-1,5-dimethyl-1H-pyrazol-3-yl)ethan-1-ol::US12599676, Example 1

SMILES CNCc1cnc2ccc(-c3ccc(F)cc3OCCc3c(C(C)O)nn(C)c3C)cn12

InChI Key InChIKey=ZEFUZRMSGUKKER-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 624868   

TargetGlycylpeptide N-tetradecanoyltransferase 1(Human)
Myricx Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 624868BDBM624868(1-(4-(2-(5-fluoro-2-(3-((methylamino)methyl)imidaz...)
Affinity DataIC50: 2.20nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2026
Entry Details
US Patent