BDBM624878 US20230322745, Compound 4

SMILES O[C@@H](CNCc1cc2nnn(CCCN3CC4(C3)CCC(CC4)OC(=O)C(O)(c3cccs3)c3cccs3)c2c2CCCc12)c1ccc(O)c2[nH]c(=O)ccc12

InChI Key InChIKey=HPLOBWSINMYAFD-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 624878   

TargetMuscarinic acetylcholine receptor M3(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624878(US20230322745, Compound 4)
Affinity DataIC50: 0.343nMAssay Description:The experiment was performed by a radioisotope affinity assay. The M3 receptor membrane protein was prepared at 10 μg/mL by Biology Department o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetBeta-2 adrenergic receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624878(US20230322745, Compound 4)
Affinity DataEC50:  2.15nMAssay Description:β1 cells (expressing human ADRB1 gene) from ICE Bioscience Inc. were grown under standard conditions. The cells were collected and diluted with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent