BDBM624966 US20230322745, Compound 39

SMILES CN(CCCn1cnc2cc(CNC[C@H](O)c3ccc(O)c4[nH]c(=O)ccc34)c3CCCc3c12)C1CC[C@@H](CC1)OC(=O)[C@@](O)(c1cccs1)c1ccc(C)s1

InChI Key InChIKey=UBDKDGUJMUUUTQ-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 624966   

TargetMuscarinic acetylcholine receptor M3(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624966(US20230322745, Compound 39)
Affinity DataIC50: 0.533nMAssay Description:The experiment was performed by a radioisotope affinity assay. The M3 receptor membrane protein was prepared at 10 μg/mL by Biology Department o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624966(US20230322745, Compound 39)
Affinity DataIC50: 1.25nMAssay Description:The M2 receptor membrane protein was prepared at 100 μg/mL by Biology Department of WuXi AppTec, and compounds were serially diluted in a 2.5-fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetBeta-2 adrenergic receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624966(US20230322745, Compound 39)
Affinity DataEC50:  21.9nMAssay Description:β1 cells (expressing human ADRB1 gene) from ICE Bioscience Inc. were grown under standard conditions. The cells were collected and diluted with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent