BDBM625015 US20230322747, Compound 37

SMILES Cn1ncc2cc(OCc3ccc(cn3)-c3nnc(o3)C(F)F)ccc12

InChI Key InChIKey=OYIMNGZETXPKGQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 625015   

TargetHistone deacetylase 6(Human)
Eikonizo Therapeutics

US Patent
LigandPNGBDBM625015(US20230322747, Compound 37)
Affinity DataIC50: 50nMAssay Description:The biochemical HDAC6 assay was performed using fluorescence detection (Fluor-De-Lys assay). In this assay, deacetylation of the Lysine residue in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetHistone deacetylase 8(Human)
Eikonizo Therapeutics

US Patent
LigandPNGBDBM625015(US20230322747, Compound 37)
Affinity DataIC50: 5.50E+4nMAssay Description:HDAC reactions were assembled in 384 well plates (Greiner) in a total volume of 20 μL as follows: HDAC proteins (and their regulatory subunit, i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent