BDBM625158 US20230322747, Compound 204::US20260102395, Compound 204
SMILES Cn1nc(ccc1=O)-c1nc2ccc(OCc3ccc(cn3)-c3nnc(o3)C(F)F)cc2o1
InChI Key InChIKey=VNDXQBCFPFXSCC-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 625158
Affinity DataIC50: 50nMAssay Description:The biochemical HDAC6 assay was performed using fluorescence detection (Fluor-De-Lys assay). In this assay, deacetylation of the Lysine residue in th...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:HDAC reactions were assembled in 384 well plates (Greiner) in a total volume of 20 μL as follows: HDAC proteins (and their regulatory subunit, i...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair