BDBM62532 MLS000028183::SMR000012523::[4-(6-Amino-9H-purin-8-yl)-piperazin-1-yl]-phenyl-methanone::[4-(6-amino-7H-purin-8-yl)-1-piperazinyl]-phenylmethanone::[4-(6-amino-7H-purin-8-yl)piperazin-1-yl]-phenylmethanone::[4-(6-amino-7H-purin-8-yl)piperazino]-phenyl-methanone::[4-(6-azanyl-7H-purin-8-yl)piperazin-1-yl]-phenyl-methanone::cid_646253

SMILES COCn1nc2cc(N3CCOc4cc(C(=O)N5CCC[C@H](C)C5)cnc43)ccn2c1=O

InChI Key InChIKey=DWBXVUDEDOEGOA-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 62532   

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Kyorin Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 62532BDBM62532(US12577217, Example 1-41)
Affinity DataIC50: 10nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2026
Entry Details
US Patent