BDBM625526 US20230322789, Compound 159::US20230322789, Example 126

SMILES COc1cc(cc(F)c1-n1nc2c(n[nH]c2cc1=O)-c1ccc2CCN(C)Cc2c1)C#N

InChI Key InChIKey=GSXVJWHXOFITGK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 625526   

LigandPNGBDBM625526(US20230322789, Compound 159 | US20230322789, Examp...)
Affinity DataIC50: 50nMAssay Description:1. HPK1 Kinase Activity Inhibition Test. The kinase activity of HPK1 is manifested as activity of autophosphorylation and phosphorylation of downstre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent