BDBM625581 US20230322792, Example I-5::trans-5-[2-(3- hydroxypiperidin- 4- yl)methylamino- pyrimidin-4-yl]-3- cyclobutyl pyrazolo[1, 5- a]pyrimidine

SMILES O[C@@H]1CNCC[C@H]1CNc1nccc(n1)-c1ccn2ncc(C3CCC3)c2n1

InChI Key InChIKey=HYUPPQURXALDHW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 625581   

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Biolexis Therapeutics

US Patent
LigandPNGBDBM625581(US20230322792, Example I-5 | trans-5-[2-(3- hydrox...)
Affinity DataIC50: 3.00E+3nMAssay Description:ADP-Glo assay kit was purchased from Promega and the CDK9/CycT1 protein and PDKtide substrate were purchased from SignalChem. Compounds of Structure ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent