BDBM626638 N-(6-(4-chloro-1H-1,2,3-triazol-1-yl)-2-fluoro-3-methoxybenzyl)-1-((6-cyclopropylimidazo[1,2-a]pyridin-2-yl)methyl)-1H-1,2,3-triazole-4-carboxamide ::US11787796, Compound I-1

SMILES COc1ccc(c(CNC(=O)c2cn(Cc3cn4cc(ccc4n3)C3CC3)nn2)c1F)-n1cc(Cl)nn1

InChI Key InChIKey=PHIYQAOFKYPKKQ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 626638   

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM626638(N-(6-(4-chloro-1H-1,2,3-triazol-1-yl)-2-fluoro-3-m...)
Affinity DataEC50: <1nMAssay Description:Example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing a fluorogenic peptide s...More data for this Ligand-Target Pair
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Date in BDB:
11/29/2023
Entry Details
US Patent