BDBM626693 1-((6-cyclopropylimidazo[1,2-a]pyridin-2-yl)methyl)-N-(2-fluoro-3-methoxy-6-(1H-tetrazol-1-yl)benzyl)-1H-pyrrole-3-carboxamide ::US11787796, Compound I-54

SMILES COc1ccc(c(CNC(=O)c2ccn(Cc3cn4cc(ccc4n3)C3CC3)c2)c1F)-n1cnnn1

InChI Key InChIKey=NXKHMPWEZDZMOZ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 626693   

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM626693(1-((6-cyclopropylimidazo[1,2-a]pyridin-2-yl)methyl...)
Affinity DataEC50: <1nMAssay Description:Example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing a fluorogenic peptide s...More data for this Ligand-Target Pair
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Date in BDB:
11/29/2023
Entry Details
US Patent