BDBM626707 1-((6-cyclopropyl-8-(oxetan-3-ylethyl)imidazo[1,2-a]pyridin-2-yl) methyl)-N-(2-fluoro-3-methoxy-6-(1H-tetrazol-1-yl) benzyl)-1H-1,2,3-triazole-4-carboxamide ::US11787796, Compound I-68

SMILES COc1ccc(c(CNC(=O)c2cn(Cc3cn4cc(cc(CC5COC5)c4n3)C3CC3)nn2)c1F)-n1cnnn1

InChI Key InChIKey=LXZBCAXSVYJLBU-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 626707   

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM626707(1-((6-cyclopropyl-8-(oxetan-3-ylethyl)imidazo[1,2-...)
Affinity DataEC50: <1nMAssay Description:Example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing a fluorogenic peptide s...More data for this Ligand-Target Pair
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Date in BDB:
11/29/2023
Entry Details
US Patent