BDBM626748 3-(2-((4-((3-choro-2-fluoro-6-(1H-tetrazol-1-yl)benzyl)carbamoyl)-1H-1,2,3-triazol-1-yl)methyl)-6-cyclopropylimidazo[1,2-a]pyridin-8-yl)propanoic Acid ::US11787796, Compound I-109

SMILES OC(=O)CCc1cc(cn2cc(Cn3cc(nn3)C(=O)NCc3c(F)c(Cl)ccc3-n3cnnn3)nc12)C1CC1

InChI Key InChIKey=QWZYJLDJHGQVCO-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 626748   

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM626748(3-(2-((4-((3-choro-2-fluoro-6-(1H-tetrazol-1-yl)be...)
Affinity DataEC50: <1nMAssay Description:Example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing a fluorogenic peptide s...More data for this Ligand-Target Pair
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Date in BDB:
11/29/2023
Entry Details
US Patent