BDBM626757 N-(6-cyano-2-fluoro-3-methoxybenzyl)-1-((8-cyano-6-cyclopropylimidazo[1,2-a]pyridin-2-yl)methyl)-1H-pyrazole-4-carboxamide ::US11787796, Compound I-118

SMILES COc1ccc(C#N)c(CNC(=O)c2cnn(Cc3cn4cc(cc(C#N)c4n3)C3CC3)c2)c1F

InChI Key InChIKey=FPKDNZOKIUDEKF-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 626757   

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM626757(N-(6-cyano-2-fluoro-3-methoxybenzyl)-1-((8-cyano-6...)
Affinity DataEC50: <1nMAssay Description:Example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing a fluorogenic peptide s...More data for this Ligand-Target Pair
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Date in BDB:
11/29/2023
Entry Details
US Patent