BDBM627079 5-[2-[Hydroxy(phenyl)methyl]benzimidazol-1-yl]-1,3-dihydrobenzimidazol-2-one::US11787802, Example 85

SMILES O=c1[nH]c2ccc(-n3c(C(O)c4ccccc4)nc4ccccc43)cc2[nH]1

InChI Key InChIKey=GVSWVXOGEHIZSH-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 627079   

TargetDNA damage-binding protein 1/Protein cereblon(Human)
C4 Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 627079BDBM627079(US11787802, Example 85 | 5-[2-[Hydroxy(phenyl)meth...)
Affinity DataKd:  3nMAssay Description:1) Optimization of measurement parameters to minimize protein consumption and to minimize the dilution effect and the DMSO content2) Titration measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
US Patent