BDBM627308 3-(2-(difluoromethoxy)-5- fluoropyridin-4-yl)-1-(3- hydroxy-3-methylbutan-2- yl)-N-(3-methyl-1,1- dioxidothietan-3-yl)-1H- pyrazolo[4,3-c]pyridine-6- carboxamide (slower eluting in AD-H column, 25% MeOH (0.1% DEA)/CO2)::US11787810, Example 133b

SMILES CC(n1nc(-c2cc(OC(F)F)ncc2F)c2cnc(cc12)C(=O)NC1(C)CS(=O)(=O)C1)C(C)(C)O

InChI Key InChIKey=QJTNEJSJDAGYKL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 627308   

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM627308(3-(2-(difluoromethoxy)-5- fluoropyridin-4-yl)-1-(3...)
Affinity DataIC50: 15nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
US Patent