BDBM627320 (S)-N-(1-(3-(3-chloro-4-cyanophenyl)- 1H-pyrazol-1-yl)propan-2-yl)-4-ethoxy- 3-(1-methyl-7-oxo-3-propyl-6,7- dihydro-1H-pyrazolo[4,3-d]pyrimidin-5- yl)benzenesulfonamide::US11787812, Compound 11

SMILES CCCc1nn(C)c2c1nc([nH]c2=O)-c1cc(ccc1OCC)S(=O)(=O)N[C@@H](C)Cn1ccc(n1)-c1ccc(C#N)c(Cl)c1

InChI Key InChIKey=QRULPAFVZLETCY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 627320   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Ildong Pharmaceutical

US Patent
LigandPNGBDBM627320(US11787812, Compound 11 | (S)-N-(1-(3-(3-chloro-4-...)
Affinity DataIC50: 100nMAssay Description:Enzymes and SubstratesCatalog Enzyme Enzyme Used Assay # Lot # (ng/reaction) SubstratePDE5A1 60050 181008-G 0.2 100 nM FAM-cGMPThe serial dilution of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
US Patent