BDBM627334 N-(1-(4-cyano-3- (trifluoromethyl)phenyl)piperidin-4-yl)- 4-ethoxy-3-(5-methyl-4-oxo-7-propyl- 3,4-dihydroimidazo[5,1-f][1,2,4]triazin- 2-yl)benzenesulfonamide::US11787812, Compound 30

SMILES CCCc1nc(C)c2n1nc([nH]c2=O)-c1cc(ccc1OCC)S(=O)(=O)NC1CCN(CC1)c1ccc(C#N)c(c1)C(F)(F)F

InChI Key InChIKey=MYMLGWVBHKYBBD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 627334   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Ildong Pharmaceutical

US Patent
LigandPNGBDBM627334(US11787812, Compound 30 | N-(1-(4-cyano-3- (triflu...)
Affinity DataIC50: 10nMAssay Description:Enzymes and SubstratesCatalog Enzyme Enzyme Used Assay # Lot # (ng/reaction) SubstratePDE5A1 60050 181008-G 0.2 100 nM FAM-cGMPThe serial dilution of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
US Patent

TargetAndrogen receptor(Human)
Ildong Pharmaceutical

US Patent
LigandPNGBDBM627334(US11787812, Compound 30 | N-(1-(4-cyano-3- (triflu...)
Affinity DataIC50: 50nMAssay Description:Human androgen receptors obtained from human LNCaP cells are used in modified HEPES buffer pH 7.4. A 70 μg (adjusted if necessary) aliquot is in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
US Patent