BDBM627512 N-(4-(4-amino-1-isopropyl-7-((1s,4s)-4-morpholinocyclohexyl)-1H-pyrazolo[4,3-c]pyridin-3-yl)-2,5-difluorophenyl)-2-fluorobenzenesulfonamide::US20230331719, Compound A14

SMILES CC(C)n1nc(-c2cc(F)c(NS(=O)(=O)c3ccccc3F)cc2F)c2c(N)ncc([C@@H]3CC[C@@H](CC3)N3CCOCC3)c12

InChI Key InChIKey=CSKVVUAUTSMHMJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 627512   

LigandPNGBDBM627512(N-(4-(4-amino-1-isopropyl-7-((1s,4s)-4-morpholinoc...)
Affinity DataIC50: 466nMAssay Description:The kinase reactions were performed in 384 well white ProxiPlate-384 Plus plates (PERKIN Elmer 6008280) using 25 mM MOPS assay buffer with 1 mM dithi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2023
Entry Details
US Patent