BDBM627524 US20230331739, Compound 1

SMILES CC1(CCCN1)c1ccc(cc1)-c1[nH]c2cc(F)cc3C(=O)NOCc1c23

InChI Key InChIKey=FBKICCXLQKLXAZ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 627524   

TargetPoly [ADP-ribose] polymerase 1(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM627524(US20230331739, Compound 1)
Affinity DataIC50: 2.30nMAssay Description:Table 4: T Universal Chemiluminescent PARP Assay kit (purchased from TREVIGEN); PBS (phosphate buffer saline, purchased from Wisent); Triton X-100 (p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2023
Entry Details
US Patent

TargetCytochrome P450 2C19(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM627524(US20230331739, Compound 1)
Affinity DataIC50: 8.33E+3nMAssay Description:Table 9: The inhibition of the test compound against different subtypes of the human cytochrome P450 isoenzyme was determined. The test compound, a s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2023
Entry Details
US Patent

TargetCytochrome P450 2D6(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM627524(US20230331739, Compound 1)
Affinity DataIC50: 1.16E+4nMAssay Description:Table 9: The inhibition of the test compound against different subtypes of the human cytochrome P450 isoenzyme was determined. The test compound, a s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2023
Entry Details
US Patent

TargetCytochrome P450 3A4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM627524(US20230331739, Compound 1)
Affinity DataIC50: 3.29E+4nMAssay Description:Table 9: The inhibition of the test compound against different subtypes of the human cytochrome P450 isoenzyme was determined. The test compound, a s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2023
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM627524(US20230331739, Compound 1)
Affinity DataIC50: 5.00E+4nMAssay Description:Table 9: The inhibition of the test compound against different subtypes of the human cytochrome P450 isoenzyme was determined. The test compound, a s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2023
Entry Details
US Patent

TargetCytochrome P450 2C9(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM627524(US20230331739, Compound 1)
Affinity DataIC50: 5.00E+4nMAssay Description:Table 9: The inhibition of the test compound against different subtypes of the human cytochrome P450 isoenzyme was determined. The test compound, a s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2023
Entry Details
US Patent