BDBM628217 US11795169, Example 13

SMILES O=c1[nH]cnc2n(cc(-c3ccc(Cn4ccnc4)cc3)c12)-c1ccccc1

InChI Key InChIKey=VXWJVRRPLDUXPZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 628217   

TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Imperial College Innovations

US Patent
LigandPNGBDBM628217(US11795169, Example 13)
Affinity DataIC50: 100nMAssay Description:Compounds of the present invention were screened for their inhibitory activity against MAP4K4, versus selected off-target hits found with early membe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2023
Entry Details
US Patent