BDBM628307 3-([4-hydroxy-1-[3-(1H-pyrazol-1-yl)butanoyl]piperidin-4-yl]methyl)-7-(4-methylphenyl)-3H,4H-imidazo[4,3-f][1,2,4]triazin-4-one::US11795171, Compound I-119::US11795171, Compound I-120::US11795171, Compound I-121
SMILES CC(CC(=O)N1CCC(O)(Cn2cnn3c(ncc3c2=O)-c2ccc(C)cc2)CC1)n1cccn1
InChI Key InChIKey=CSJWULTZZLZNMC-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 628307
Affinity DataIC50: 600nMAssay Description:Each assay was performed in a final volume of 15 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Each assay was performed in a final volume of 15 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human USP7 using ubiquitin-Rh110 as substrate incubated for 23 to 45 mins by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.50E+3nMAssay Description:Each assay was performed in a final volume of 15 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair