BDBM628384 3-((1-(4-((3,5-dimethyl-1H-pyrazol-1-yl)methyl)benzoyl)-4-hydroxypiperidin-4-yl)methyl)pyrrolo[2,1-f][1,2,4]triazin-4(3H)-one::US11795171, Compound I-69

SMILES Cc1cc(C)n(Cc2ccc(cc2)C(=O)N2CCC(O)(Cn3cnn4cccc4c3=O)CC2)n1

InChI Key InChIKey=CNJBMGKKOOFWAC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 628384   

TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Valo Health

US Patent
LigandPNGBDBM628384(3-((1-(4-((3,5-dimethyl-1H-pyrazol-1-yl)methyl)ben...)
Affinity DataIC50: 600nMAssay Description:Each assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2023
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Valo Health

US Patent
LigandPNGBDBM628384(3-((1-(4-((3,5-dimethyl-1H-pyrazol-1-yl)methyl)ben...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human USP7 using ubiquitin-Rh110 as substrate incubated for 23 to 45 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed