BDBM628462 US11795173, Example 30

SMILES CNC(=O)c5ccc(N4CCN(Cc3ccc2c([nH]c(=O)c1ccoc12)c3F)CC4)c(F)n5

InChI Key InChIKey=IXGZNTGACBFAFA-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 628462   

TargetPoly [ADP-ribose] polymerase 1(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 628462BDBM628462(US11795173, Example 30 | US20250215013, Example 44)
Affinity DataIC50: 0.410nMAssay Description:The solution of recombinant poly(ADP-ribose) polymerase 1 and 2 (PARP1 and PARP2) (40 ng enzyme/well) and the compounds to be tested were mixed, resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent

TargetProtein cereblon/PARP2(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 628462BDBM628462(US11795173, Example 30 | US20250215013, Example 44)
Affinity DataIC50: 898nMAssay Description:The solution of recombinant poly(ADP-ribose) polymerase 1 and 2 (PARP1 and PARP2) (40 ng enzyme/well) and the compounds to be tested were mixed, resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 628462BDBM628462(US11795173, Example 30 | US20250215013, Example 44)
Affinity DataIC50: 1.65E+4nMAssay Description:A PDE3A fluorescence polarization (FP) assay in a multi-step format was performed using black, round bottom 384-well plates (Corning, 4514). The test...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent