BDBM628566 US20230339882, Example A55

SMILES CN(CC#Cc1cnc(N2CCC3(Cc4ccccc4[C@H]3N)CC2)c(CO)n1)c1ccc(cc1)C(N)=O

InChI Key InChIKey=XNDYIGYLCPCNBU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 628566   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM628566(US20230339882, Example A55)
Affinity DataIC50: 2.70nMAssay Description:SHP2 is allosterically activated by binding of a bis-tyrosyl-phosphorylated peptide to its Src homology 2 (SH2) domain. This later activation step re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent