BDBM628568 US20230339882, Example A57

SMILES CP(C)(=O)c1ccc(OCC#Cc2cnc(N3CCC4(Cc5ccccc5[C@H]4N)CC3)c(CO)n2)cc1

InChI Key InChIKey=SQMXNNHLWWPPRL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 628568   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM628568(US20230339882, Example A57)
Affinity DataIC50: 4.30nMAssay Description:SHP2 is allosterically activated by binding of a bis-tyrosyl-phosphorylated peptide to its Src homology 2 (SH2) domain. This later activation step re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM628568(US20230339882, Example A57)
Affinity DataIC50: 2.00E+4nMAssay Description:When the whole-cell seal is formed, wait for the current to stabilize for 2 minutes (the current decay is less than 5% within 5 minutes, and the tail...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent