BDBM628573 US20230339882, Example A59

SMILES N[C@@H]1c2ccccc2CC11CCN(CC1)c1ncc(nc1CO)C#CCOc1cccc(CC(N)=O)c1

InChI Key InChIKey=QNXYOIMKVPJYBB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 628573   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM628573(US20230339882, Example A59)
Affinity DataIC50: 1.10nMAssay Description:SHP2 is allosterically activated by binding of a bis-tyrosyl-phosphorylated peptide to its Src homology 2 (SH2) domain. This later activation step re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM628573(US20230339882, Example A59)
Affinity DataIC50: 2.60E+4nMAssay Description:When the whole-cell seal is formed, wait for the current to stabilize for 2 minutes (the current decay is less than 5% within 5 minutes, and the tail...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent