BDBM628693 (S)-(3-(1-amino-1,3-dihydrospiro[ indene-2,4'-piperidin]-1'-yl)-6-(3-( benzo[d][1,3]dioxyol-5-oxy)prop-1-yn-1-yl)pyrazin-2-yl)methanol::US20230339882, Example A28
SMILES N[C@@H]1c2ccccc2CC11CCN(CC1)c1ncc(nc1CO)C#CCOc1ccc2OCOc2c1
InChI Key InChIKey=CRMQMDJGXHWCOI-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 628693
Affinity DataIC50: 1.5nMAssay Description:SHP2 is allosterically activated by binding of a bis-tyrosyl-phosphorylated peptide to its Src homology 2 (SH2) domain. This later activation step re...More data for this Ligand-Target Pair
