BDBM628867 US20230339890, Compound 145::US20230339890, Compound 146

SMILES CC(C)(C)OC(=O)NC1CCC(CN(C[C@@H](O)c2cccnc2)C(=O)Cc2ccc(nc2)C(F)(F)F)CC1

InChI Key InChIKey=GBJMZLMIAWJRBK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 628867   

TargetLanosterol 14-alpha demethylase(Human)
Kineta

US Patent
LigandPNGBDBM628867(US20230339890, Compound 145 | US20230339890, Compo...)
Affinity DataIC50: 100nMAssay Description:Method: Recombinant human CYP51A1 (lanosterol-14a-demethylase) enzyme was coexpressed with CYP reductase in bacterial membranes and the fluorescent s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent

TargetLanosterol 14-alpha demethylase(Human)
Kineta

US Patent
LigandPNGBDBM628867(US20230339890, Compound 145 | US20230339890, Compo...)
Affinity DataIC50: 550nMAssay Description:Method: Recombinant human CYP51A1 (lanosterol-14a-demethylase) enzyme was coexpressed with CYP reductase in bacterial membranes and the fluorescent s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent