BDBM628909 US20230339891, Example 19

SMILES CC(C)n1cc(C(=O)Nc2ccc(Oc3ccnc(Nc4ccc(cn4)S(N)(=O)=O)c3)c(F)c2)c(=O)n(-c2ccc(F)cc2)c1=O

InChI Key InChIKey=ACJPYAYXMSVFMW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 628909   

TargetTyrosine-protein kinase receptor UFO(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM628909(US20230339891, Example 19)
Affinity DataIC50: 1.60nMAssay Description:Binding assays contained 1 nM kinase (GST-MERTK 578-872, HIS-AXL 473-End, or GST-TYRO 451-890), 0.2 nM terbium labelled antibody (anti-GST or anti-HI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent

TargetTyrosine-protein kinase Mer(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM628909(US20230339891, Example 19)
Affinity DataIC50: 4.40nMAssay Description:Binding assays contained 1 nM kinase (GST-MERTK 578-872, HIS-AXL 473-End, or GST-TYRO 451-890), 0.2 nM terbium labelled antibody (anti-GST or anti-HI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent