BDBM628991 US20230339891, Example 105

SMILES Fc1ccc(cc1)-n1c(=O)c(cn(C2CC2)c1=O)C(=O)Nc1ccc(Oc2ccnc(Nc3ccnc(n3)N3CCCC3)c2)c(F)c1

InChI Key InChIKey=VXVHXDKIVTYZHG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 628991   

TargetTyrosine-protein kinase Mer(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM628991(US20230339891, Example 105)
Affinity DataIC50: 1.40nMAssay Description:Binding assays contained 1 nM kinase (GST-MERTK 578-872, HIS-AXL 473-End, or GST-TYRO 451-890), 0.2 nM terbium labelled antibody (anti-GST or anti-HI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent

TargetTyrosine-protein kinase receptor UFO(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM628991(US20230339891, Example 105)
Affinity DataIC50: 2.30nMAssay Description:Binding assays contained 1 nM kinase (GST-MERTK 578-872, HIS-AXL 473-End, or GST-TYRO 451-890), 0.2 nM terbium labelled antibody (anti-GST or anti-HI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent