BDBM629299 (1S,2S)-2-fluoro-N-(5-(4-methyl-1H-pyrrolo[2,3-b]pyridin-5-yl)pyrazolo[1,5-a]pyridin-2-yl)cyclopropane-1-carboxamide::US20230339978, Example 19::US20230339978, Example 9
SMILES Cc1c(cnc2[nH]ccc12)-c1ccn2nc(NC(=O)[C@@H]3C[C@@H]3F)cc2c1
InChI Key InChIKey=YIUOPZRKRRRSTC-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 629299
Affinity DataIC50: 2.40nMAssay Description:c-Abl kinase activity was measured by Promega s ADP-Glo Assay. In this assay, His-tagged recombinant human ABL1 (0.25 ng/ l) is incubated with 5 L of...More data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:c-Abl kinase activity was measured by Promega s ADP-Glo Assay. In this assay, His-tagged recombinant human ABL1 (0.25 ng/ l) is incubated with 5 L of...More data for this Ligand-Target Pair
Affinity DataIC50: 8.77nMAssay Description:GST-tagged recombinant human RIPK2(25 ng) is incubated with 5 µL of compounds (0.5% DMSO), 5 µL of MBP (0.5 µg/µl) and 5 µL of ATP (25 µM) in buffer ...More data for this Ligand-Target Pair
Affinity DataIC50: 11.4nMAssay Description:GST-tagged recombinant human RIPK2(25 ng) is incubated with 5 µL of compounds (0.5% DMSO), 5 µL of MBP (0.5 µg/µl) and 5 µL of ATP (25 µM) in buffer ...More data for this Ligand-Target Pair