BDBM629958 US20230340011, Example 257.

SMILES COC1=C2C[C@@H](O)CC[C@]2(C)[C@H]2CC[C@]3(C)[C@H](CC[C@H]3[C@@H]2C1)[C@H](C)COc1ncccc1CO

InChI Key InChIKey=CMBRKTLQQIQDJK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 629958   

TargetSterol regulatory element-binding protein 2(Human)
Asteroid Therapeutics

US Patent
LigandPNGBDBM629958(US20230340011, Example 257.)
Affinity DataIC50: 125nMAssay Description:10,000 cells/well of the PathHunter U2OS SREBP-2 Nuclear Translocation Cell Line are plated in quadruplicate on 384 well plates in 20 μL of Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent

TargetOxysterols receptor LXR-beta(Human)
Asteroid Therapeutics

US Patent
LigandPNGBDBM629958(US20230340011, Example 257.)
Affinity DataIC50: 1.00E+4nMAssay Description:PathHunter NHR CHO cells stably transfected with tagged full-length human LXRβ and a nuclear fusion protein containing Steroid Receptor Co-activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2023
Entry Details
US Patent