BDBM630987 (4S)-N-{(R or S)- (3- chloro-2,4- difluorophenyl)[6- (trifluoromethoxy)pyri- din-3-yl]methyl}-2- oxoimidazolidine-4- carboxamide::US11802122, Example 24A::US11802122, Example 24B

SMILES Fc1ccc(C(NC(=O)[C@@H]2CNC(=O)N2)c2ccc(OC(F)(F)F)nc2)c(F)c1Cl

InChI Key InChIKey=SWVVATLQSDSVEQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 630987   

TargetSodium channel protein type 8 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM630987(US11802122, Example 24A | US11802122, Example 24B ...)
Affinity DataIC50: 3.10nMAssay Description:The following buffers were used for the Qube recordings: External buffer for NaV1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetSodium channel protein type 8 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM630987(US11802122, Example 24A | US11802122, Example 24B ...)
Affinity DataIC50: 41nMAssay Description:The following buffers were used for the Qube recordings: External buffer for NaV1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent