BDBM631015 (4S)-N-[(R or S)-(3- chloro-2,4-di- fluoro-phenyl)(3,3- dimethylcyclobutyl)meth- yl]-2- oxoimidazolidine-4- carboxamide::US11802122, Example 30A::US11802122, Example 30B

SMILES CC1(C)CC(C1)C(NC(=O)[C@@H]1CNC(=O)N1)c1ccc(F)c(Cl)c1F

InChI Key InChIKey=SUTRAXOAVVBEAL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 631015   

TargetSodium channel protein type 8 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM631015(US11802122, Example 30A | US11802122, Example 30B ...)
Affinity DataIC50: 4.60nMAssay Description:The following buffers were used for the Qube recordings: External buffer for NaV1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetSodium channel protein type 8 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM631015(US11802122, Example 30A | US11802122, Example 30B ...)
Affinity DataIC50: 458nMAssay Description:The following buffers were used for the Qube recordings: External buffer for NaV1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent