BDBM631365 6-(2-Chloro-4-methylphenyl)-2-[[3-(trifluoromethyl)piperazin-1-yl]methyl]-1H-benzimidazole-4-carboxylic acid::US20230348398, Example 11

SMILES Cc1ccc(c(Cl)c1)-c1cc(C(O)=O)c2nc(CN3CCNC(C3)C(F)(F)F)[nH]c2c1

InChI Key InChIKey=HTIVOHCLUMIGJA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 631365   

TargetCyclic GMP-AMP synthase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM631365(US20230348398, Example 11 | 6-(2-Chloro-4-methylph...)
Affinity DataIC50: 600nMAssay Description:All compounds were prepared as 10 mM stock solutions in DMSO and a 16 pt dilution series in DMSO with a dilution factor of 2.5 was prepared. 1 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent