BDBM631366 6-(2-Chloro-4-methylphenyl)-2-[(4-methyl-2-oxopiperazin-1-yl)methyl]-1H-benzimidazole-4-carboxylic acid::US20230348398, Example 12

SMILES CN1CCN(Cc2nc3c(cc(cc3[nH]2)-c2ccc(C)cc2Cl)C(O)=O)C(=O)C1

InChI Key InChIKey=GRMJIPRBPQCCCE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 631366   

TargetCyclic GMP-AMP synthase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM631366(US20230348398, Example 12 | 6-(2-Chloro-4-methylph...)
Affinity DataIC50: 1.14E+3nMAssay Description:All compounds were prepared as 10 mM stock solutions in DMSO and a 16 pt dilution series in DMSO with a dilution factor of 2.5 was prepared. 1 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent